What is Food Intolerance (Non-IgE mediated Food Hypersensitivity)

In food allergy, an abnormal immune system response results in the body making antibodies to 'fight off' a food.  However, some people suffer symptoms after eating certain foods even when they are not producing antibodies against them.  A variety of different mechanisms can cause foods to affect people in this way; collectively these are known as non-IgE mediated food hypersensitivity, or as most commonly known food intolerance.

Food intolerance is much more common than food allergy.  The onset of symptoms is usually slower and may be delayed by many hours after eating the offending food.  The symptoms may also last for several hours, even into the next day.  Intolerance to several foods or a group of foods is not uncommon, and it can be much more difficult to decide whether food intolerance is the cause of chronic illness, and which foods or substances may be responsible.

In allergy, the patient cannot usually tolerate even a small amount of the offending food without suffering symptoms, as it only takes a tiny amount to trigger a response from the immune system.  With intolerance, most people can tolerate a reasonable amount of the food, but if they eat too much (or too often) they get symptoms because their body cannot keep up to speed with breaking down the constituents of the food.

The symptoms of food intolerance are varied and may include the following effects:
  • fatigue
  • gingivitis,
  • hives
  • rhinitis,
  • hallucination,
  • mood changes,
  • irritability,
  • hyperactivity (school problems)
  • epilepsy cephalgia (migraine, neuralgia, vertigo, convulsion)
  • dysautonomia, psychic dysregulation
  • epilepsy
  • hypertension, angina, heart failure, tachycardia, spasm, and other problems of cramps in the the lower limbs
  • obesity, metabolic dysfunction.
  • peptic ulcer,
  • ulcerative colitis
  • Crohn's disease,
  • irritable bowel syndrome,
  • dyspepsia, constipation, diarrhea, mouth ulcer.
  • renal failure,
  • chronic cystitis,
  • enuresis,
  • vaginal infections
  • sterility, amenorrhea, metrorrhagia,
  • hypo-hyper thyroidism
  • arthritis, osteoarthritis,
  • multiple sclerosis, carpal tunnel
  • fibromyalgia
  • eczema, urticaria, dermatitis, acne, psoriasis
  • asthma
  • hypo-hyperactivity
  • autism
  • schizophrenia

Different causes

How is Food Intolerance recognised?


The ImuPro Test

The ImuPro method for eliminating intolerances